Table 1 List of genes that are most upregulated during growth with AMS.
From: A novel siderophore system is essential for the growth of Pseudomonas aeruginosa in airway mucus
PA number | Gene | Fold changea | Target Description |
---|---|---|---|
PA3446 | — | 56.63 | conserved hypothetical protein |
PA3600 | — | 49.03 | conserved hypothetical protein/Translation, post-translational modification |
PA0284 | — | 36.28 | hypothetical protein |
PA4063 | — | 35.15 | hypothetical protein |
PA3601 | — | 24.27 | conserved hypothetical protein/Translation, post-translational modification |
PA2359 | — | 21.93 | probable transcriptional regulator |
PA3450 | — | 21.63 | probable antioxidant protein/adaptation, protection |
PA4570 | — | 19.36 | hypothetical protein |
PA4471 | — | 18.45 | hypothetical protein |
PA2161 | — | 16.99 | hypothetical protein |
PA0802 | — | 16.82 | hypothetical protein/Membrane proteins |
PA5536 | dksA2 | 15.69 | DnaK suppressor protein |
PA2062 | — | 15.52 | probable pyridoxal-phosphate dependent enzyme/Putative enzymes |
PA1911 | femR | 13.79 | sigma factor regulator |
PA2033 | — | 11.83 | hypothetical protein |
PA1905 | phzG2 | 11.29 | probable pyridoxamine 5′-phosphate oxidase/Secreted Factors |
PA4230 | pchB | 10.98 | salicylate biosynthesis protein PchB/Transport of small molecules; Secreted Factors |
PA1373 | fabF2 | 10.86 | 3-oxoacyl-acyl carrier protein synthase II/Fatty acid and phospholipid metabolism |
PA4103 | — | 10.61 | hypothetical protein |
PA4224 | pchG | 10.61 | pyochelin biosynthetic protein PchG |
PA2570 | lecA | 10.15 | PA-I galactophilic lectin/Adaptation, protection; Motility & Attachment Cell wall |
PA2786 | — | 9.98 | hypothetical protein |
PA1300 | — | 9.66 | probable sigma-70 factor, ECF subfamily/Transcriptional regulators |
PA3381 | — | 9.55 | probable transcriptional regulator/Transcriptional regulators |
PA0993 | cupC2 | 9.36 | chaperone CupC2/probable pili assembly chaperone/Motility & Attachment |
PA4033 | mucE | 9.01 | hypothetical protein |
PA4837 | — | 8.95 | probable outer membrane protein precursor/Membrane proteins |
PA4516 | — | 8.93 | hypothetical protein |
PA4834 | — | 8.33 | hypothetical protein/Membrane proteins |
PA4226 | pchE | 8.27 | dihydroaeruginoic acid synthetase/Transport of small molecules; Secreted Factors |
PA0790 | — | 8.05 | hypothetical protein/Membrane proteins |
PA3126 | ibpA | 7.92 | heat-shock protein LbpA/Chaperones & heat shock proteins |
PA1312 | — | 7.84 | probable transcriptional regulator/Transcriptional regulators |
PA2426 | pvdS | 7.76 | sigma factor PvdS/Transcriptional regulators |
PA4225 | pchF | 7.23 | pyochelin synthetase/Transport of small molecules; Secreted Factors |