Figure 1
From: MeSiC: A Model-Based Method for Estimating 5 mC Levels at Single-CpG Resolution from MeDIP-seq

CpG density-dependent bias in MeDIP-seq data.
We divided the genome into 1-kb non-overlapping windows and calculated average 5 mC level, RPM value and CpG density for each window. We classified the windows into 18 groups according to CpG density and we compared (A) the distribution of 5 mC levels and (B) the distribution of RPM values among these groups.