Figure 3
From: MeSiC: A Model-Based Method for Estimating 5 mC Levels at Single-CpG Resolution from MeDIP-seq
MeSiC enabled to accurately predict 5 mC levels.
(A) For each genomic element, we evaluated the performance of MeSiC on all 24 chromosomes. (B) The UCSC Browser screenshot of DNMT3A illustrating 5 mC levels (red), MeSiC predictions (green) and MeDIP-seq reads coverage (blue). (C) The UCSC Browser screenshot showing 5 mC levels (top track) and MeSiC predictions (bottom track) in a 100-kb sliding window on chromosome 2. (D) The distribution of absolute differences between MeSiC predictions and 5 mC levels in different CpG-density groups.
