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Figure 2

From: Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels

Figure 2

Endogenous Ca2+ -activated chloride currents in naïve X. laevis (•) and X. borealis () oocytes.

Representative families of whole-cell currents elicited by steps from −120 mV to +100 mV in 20-mV increments in oocytes from (a) X. laevis and (b) X. borealis (holding potential of −100 mV). (c) Peak amplitude as measured at the end of a 2 s pulse to +100 mV. A significant difference was observed between the two species (unpaired t-test, P = 8.3 × 10−5). Each data point indicates recording from a single oocyte (n = 22). Several oocytes were used from each of five individual frogs of each species. Data are presented as mean (dashed line) and 95% confidence intervals.

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