Table 1 Clinical characteristic of the study participants.

From: Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue

Characteristic

Baseline

12 months post-surgery

P-value

Body weight (kg)

152 ± 36.3

110 ± 21.1

5.6E-05

BMI (kg/m2)

53.1 ± 10.1

38.6 ± 6.69

3.2E-06

Fasting plasma glucose (FPG) (mmol/l)

6.87 ± 1.81

5.16 ± 0.71

4.0E-04

Fasting plasma insulin (FPI) (pmol/l)

191 ± 145

66.5 ± 46.1

9.6E-04

HbA1c (%)

6.23 ± 0.93

5.31 ± 0.50

3.6E-04

Triacylglycerol (TG) (mmol/l)

1.78 ± 0.56

1.10 ± 0.36

4.2E-05

Free fatty acids (FFA) (mmol/l)

0.93 ± 0.25

0.37 ± 0.20

5.1E-10

Total cholesterol (mmol/l)

4.97 ± 0.93

4.73 ± 0.74

0.34

LDL-cholesterol (mmol/l)

3.14 ± 0.67

2.97 ± 0.84

0.51

HDL-cholesterol (mmol/l)

1.04 ± 0.31

1.39 ± 0.28

4.8E-04

C-reactive protein (CrP) (mg/l)

6.11 ± 3.26

2.26 ± 1.39

2.9E-05

Alanine aminotransferase (μkat/l)

0.83 ± 0.41

0.48 ± 0.25

1.8E-03

Aspartate transaminase (μkat/l)

0.66 ± 0.33

0.39 ± 0.16

2.3E-03

γ-Glutamyl transferase (μkat/l)

0.82 ± 0.63

0.41 ± 0.18

8.5E-03

Leptin (ng/ml)

57.9 ± 16.9

33.0 ± 10.6

1.8E-06

Adiponectin (μg/ml)

4.88 ± 3.04

10.3 ± 2.25

9.1E-08

  1. Data are shown as means ± SD. P-value indicates significance-level of difference before and after weight loss for the 22 individuals undergoing bariatric surgery.