Table 2 Origins and properties of investigated reductases.

From: Highly Efficient CYP167A1 (EpoK) dependent Epothilone B Formation and Production of 7-Ketone Epothilone D as a New Epothilone Derivative

Name

Organism

Amino

Molecular

Literature

acids

weight

[kDa]

AdR

Bos taurus

492

50.3

69

Arh1

S. pombe

469

51.4

29

FdR_B

S. cellulosum So ce56

244

26.7

31

FNR

C. reinhardtii

320

36.5

38, 70, 71, 72

  1. The listed reductases contain flavin adenine dinucleotide and use both NADPH and NADH as a cofactor (Arh1 and FdR_B) with the preference for NADPH for FdR_B31, while AdR and FNR use NADPH only.