Table 1 Characteristics of the study population across percentile increments of cord blood 25(OH)D levels.

From: Cord Blood 25-hydroxyvitamin D and Fetal Growth in the China-Anhui Birth Cohort Study

Characteristics

Percentile of 25(OH)D level in cord blood

P-values*

1–10 (n = 147)

11–20 (n = 151)

21–30 (n = 149)

31–40 (n = 149)

41–50 (n = 149)

51–60 (n = 149)

61–70 (n = 150)

71–80 (n = 148)

81–90 (n = 150)

91–100 (n = 149)

Cord blood 25(OH) , nmol/L)

 Mean (SD)

12.08 (3.07)

19.37 (1.66)

24.50 (1.45)

29.54 (1.43)

34.05 (1.09)

38.58 (1.43)

43.66 (1.58)

50.25 (2.11)

59.34 (3.76)

82.78 (13.99)

 

 Range

6.06–16.59

16.62–22.17

22.20–27.15

27.18–32.01

32.07–36.03

36.06–41.07

41.10–46.71

46.83–53.85

53.91–66.72

66.78–119.64

 

Sociodemographic characteristics

 Maternal age, y, mean (SD)

27.00 (3.42)

27.72 (3.68)

27.42 (3.51)

28.15 (3.96)

27.74 (3.51)

27.56 (3.42)

27.63 (3.74)

27.93 (3.78)

28.01 (4.02)

27.34 (3.44)

0.067

 Maternal education <9 years, n (%)

33(22.4)

34(22.5)

33(22.1)

36(24.2)

29(19.5)

24(16.1)

25(16.7)

33(22.3)

29(19.3)

34(22.8)

0.209

 Family monthly income <2000 RMB/yuan, n (%)

27(18.4)

25(16.6)

17(11.4)

21(14.1)

22(14.8)

19(12.8)

25(16.7)

30(20.3)

17(11.3)

22(14.8)

0.613

Perinatal health status

 Prepregnancy BMI, mean (SD)

20.20 (2.73)

20.25 (2.27)

20.37 (2.64)

20.10 (2.13)

19.80 (2.36)

20.03 (2.22)

20.04 (2.53)

20.55 (2.57)

20.27 (2.51)

19.97 (2.08)

0.547

 GWG, kg, mean (SD)

16.68 (4.63)

17.19 (5.31)

17.43 (5.19)

16.74 (4.47)

16.93 (5.39)

17.02 (5.07)

16.79 (4.59)

17.01 (4.32)

16.24 (4.58)

15.53 (4.73)

0.150

 Multipara, n (%)

15(10.2)

26(17.2)

14(9.4)

22(14.8)

22(14.8)

24(16.1)

22(14.7)

16(10.8)

22(14.7)

133(10.7)

0.637

 Pregnancy complicationsa, n (%)

23(15.6)

33(21.9)

22(14.8)

28(18.8)

23(15.4)

22(14.8)

18(12.0)

16(10.8)

23(15.3)

18(12.1)

0.055

Prepregnancy lifestyleb

 Maternal alcohol consumptionc, n (%)

18(12.2)

30(19.9)

17(11.4)

25(16.8)

20(13.4)

25(16.8)

29(19.3)

24(16.2)

22(14.7)

15(10.4)

0.537

 Paternal smokingd, n (%)

35(23.8)

29(19.2)

38(25.5)

35(23.5)

27(18.1)

40(26.8)

29(19.3)

35(23.6)

29(19.3)

39(26.2)

0.640

 Paternal alcohol consumptionc, n (%)

114(77.6)

117(77.5)

127(85.2)

116(77.9)

111(74.5)

120(80.5)

117(78.0)

126(85.1)

127(84.7)

124(83.2)

0.118

Birth outcomes

 Male infant, n (%)

62(42.2)

86(57.0)

73(49.0)

80(53.7)

76(51.0)

78(52.3)

85(56.7)

81(54.7)

87(58.0)

83(55.7)

0.027

 Gestational weeks, w, mean (SD)

38.77 (1.98)

38.68 (1.47)

39.04 (1.37)

39.00 (1.22)

38.93 (1.57)

38.98 (1.41)

38.96 (1.28)

39.13 (1.40)

38.89 (1.29)

38.77 (1.60)

0.204

 Birth weight, g, mean (SD)

3235.6 (533.4)

3351.4 (455.4)

3382.3 (452.2)

3447.6 (412.3)

3460.1 (435.6)

3452.3 (475.6)

3436.5 (416.0)

3412.8 (437.4)

3342.4 (441.1)

3310.4 (425.7)

0.262

 SGA, n (%)

22 (15.0)

17 (11.3)

16 (10.7)

9 (6.0)

8 (5.4)

9 (6.0)

10 (6.7)

11 (7.4)

14 (9.3)

17 (11.4)

0.155

 Birth during summer or autumn, n (%)

0 (0.0)

17 (11.3)

45 (30.2)

66 (44.3)

85 (57.0)

90 (60.4)

105 (70.0)

116 (78.4)

128 (85.3)

140 (94.0)

<0.001

  1. Abbreviation: 25(OH)D, 25-hydroxyvitamin D; BMI, body mass index; GWG, gestational weight gain; SGA, small for gestational age.
  2. aPregnancy complications included diabetes mellitus, hypertension, abnormal heart function, glandula thyreoidea disease, intrahepatic cholestasis of pregnancy, moderate and severe anemia.
  3. bPrepregnancy lifestyle means lifestyle during up to 6 months before pregnancy.
  4. cAlcohol consumption was defined as any alcohol consumption.
  5. dPaternal smoking was defined as more than 6 cigarettes daily.
  6. *Test for trend based on Mantel-Haenszel chi-square test for categorical variables and linear regression for continuous variables.