Figure 3
From: The antiviral drug ganciclovir does not inhibit microglial proliferation and activation
The effects of ganciclovir were investigated in the vesicular stomatitis virus (VSV) encephalitis model.
Neuroinflammation was demonstrated by T cell infiltration in the cerebral cortex (A,C). Total microglia numbers were analyzed by Iba1 staining, while proliferating microglia were visualized by double staining for Iba1/Ki67 (B,C). No effects of ganciclovir on T cell infiltration and microglial numbers could be observed between groups. Each bar represents the mean ± SEM, n = 5 per time point and group.
