Figure 2
From: Profiling RNA editing in human tissues: towards the inosinome Atlas
Classification of RNA editing sites.
(A) Fraction of A-to-I sites discovered by our computational approach including events in hyper-edited reads that are currently disregarded by main RNA-Seq aligners. (B) Partitioning of detected RNA editing sites in Alu elements (ALU), other repetitive regions (REP-NON-ALU) and nonrepetitive regions (NON-REP). According to previous large-scale investigations, the vast majority of RNA editing sites resides in repetitive regions (97%). (C) Genomic localization of detected editing sites. (D) Fraction of synonymous and nonsynonymous A-to-I events occurring in ALU and nonrepetitive regions of open reading frames.
