Figure 1 | Scientific Reports

Figure 1

From: MicroRNA panels as disease biomarkers distinguishing hepatitis B virus infection caused hepatitis and liver cirrhosis

Figure 1

Profiling of miRNAs.

(a) Study design, Chronic hepatitis B (CHB) patients, liver cirrhosis (LC) patients and healthy controls (HC) were recruited for the discovery (15/group), training (50/group), validation (100/group) phases and the blinded test. Individual miRNAs in the plasma were measured using quantitative realtime-PCR assay. (b) Profiling of miRNAs in training phase of HBV infected patients. (c) Profiling of miRNAs in validation phase of HBV infected patients. MiRNAs with significantly different expression levels between CHB, LC and HC of training phase (b) and validation phase (c) were shown. MiRNAs up indicates up-regulation while down meant down-regulation. Lined showed same miRNAs had different expression levels in different groups.

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