Figure 1
From: Novel insights from 3D models: the pivotal role of physical symmetry in epithelial organization
Mechanical properties of EP and OP.
(a) Schematic representation of the overlay and embedded culture methods. Red corresponds to β4-integrin, green to cadherin and light blue circles are representative of the nuclei. (b) Frequency spectra for the complex shear modulus G of water, OM and the Matrigel bed as determined by AMR. G’ and G” frequency sweeps of 10, 20, 30, 40, 50, 70, 80, 90 and 100 Hz are shown. Each line represents a different bead. 10, 13 and 13 beads were measured for water, OM and Matrigel, respectively. Statistical significance was determined with one-sided Mann-Whitney U tests with p-values < 0.025 deemed significant.
