Figure 1
From: The invasive potential of Giardia intestinalis in an in vivo model
Light microscopy images of the duodenal villi of the gerbils at different ages: gerbils inoculated with the HGINV isolate (A1–A5), the WB reference isolate (B1–B5) and the control group (C1–C5). A2 shows a trophozoite with a typical crescent shape embedded in the tissue at the level of the enterocytes nuclei. A3 shows three trophozoites inside a lacteal vessel. A4 shows damage to the epithelium and the nuclei of cells in that area; additionally one trophozoite is entering at the centre of the villus (CV) and another is already inside. The epithelium had regenerated by 90 days (A5); inoculation with WB did not damage the epithelium (B1–B5). Giardia trophozoites embedded in the tissue (arrowheads); trophozoites (T); Lumen (L); brush border (→); duodenal epithelium (DE); goblet cells (GC); lacteal vessel (LA); submucosa (SUB); muscular (M); myenteric plexus neuron (⇒); blood vessel (BV); arteriole (AR); cell lysis (CL). Sections (0.5 μm) stained with toluidine blue; 100X; scale bar 10 μm. Acknowledged to Gonzalez-Maciel A. by images.
