Figure 1 | Scientific Reports

Figure 1

From: Alloreactive CD154-expressing T-cell subsets with differential sensitivity to the immunosuppressant, belatacept: potential targets of novel belatacept-based regimens

Figure 1

(A) Histogram showing the effect of belatacept on CD154+T-cells. Figure 1B. The effect of belatacept concentrations on nine CD154+T-cell subsets is modeled with best-fit four-parameter log-logistic function. Insets show calculated EC50. Similar analyses have been performed for nine subsets of each of the Th, Tc and double negative (Dn, CD3+CD4−CD8−) T-cells.

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