Figure 3 | Scientific Reports

Figure 3

From: Alloreactive CD154-expressing T-cell subsets with differential sensitivity to the immunosuppressant, belatacept: potential targets of novel belatacept-based regimens

Figure 3

Heatmap from hierarchical clustering analysis shows Spearman correlations between EC50 values for each CD154+T-cell subset with frequencies of each of 36 T-cell subsets for 20 responders.

Spearman rho values range from −0.6 (green) to 0.6 (red). Tc EC50 is correlated with frequencies of several T-cell subsets. ThM28- frequencies are correlated with EC50 of several T-cell subsets. T = T-cell, Tc = T-cytotoxic cell, Th = T-helper cell, M = memory, N = naïve, Dn = double negative T-cell (CD3 + CD4-CD8-).

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