Figure 4 | Scientific Reports

Figure 4

From: Alloreactive CD154-expressing T-cell subsets with differential sensitivity to the immunosuppressant, belatacept: potential targets of novel belatacept-based regimens

Figure 4

Plots showing mean Immunoreactivity Index (IR) values for T-cytotoxic Memory (TcM), T- cytotoxic (Tc) and T-helper CD28 negative (Th + 28−) cells which express CD154 in blood samples from 11 children who have received liver or intestine transplantation.

For each subset, mean values are shown for rejectors (n = 4) and non-rejectors (n = 7). Significantly greater IR values are seen in rejectors compared with non rejectors for the TcM and Tc subsets but not the ThM + 28− subset. Subjects received tacrolimus based immunosuppression and not belatacept.

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