Figure 1 | Scientific Reports

Figure 1

From: Notch Signaling in Inflammation-Induced Preterm Labor

Figure 1

DLL-1 ligand, Notch1 and Hes1 increase in decidual macrophages during PGN+poly(I:C)-induced preterm labor.

(A) Co-localization of macrophages stained with F4/80 (green) and DLL-1 (red) and merged images of F4/80 and DLL-1 in uterine decidua from mice treated with either PBS or PGN+poly(I:C). N = 4-5 animals per group. Six sections per animal were analyzed. Original magnification: 400 X. Bars: 10 μm (B) The mRNA expression of DLL-1, Notch1 and Hes1 in decidual macrophages recovered from mice on day 14.5 of normal pregnancy, cultured ex vivo and treated with PBS or PGN+poly(I:C) for 2 h. N = 3 each group. Error bars = ±SEM. **P ≤ 0.01 Significant difference vs. PBS.

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