Figure 6

Inhibition of Notch signaling suppresses inflammatory responses in decidual cells.
Pro-inflammatory and anti-inflammatory cytokines and chemokine were measured by Luminex assay in protein extracted from decidual cells recovered from mouse on day 14.5 of pregnancy, cultured ex vivo and treated with PBS and PGN+poly(I:C) for 2 h, followed by treatment with either control or GSI for 10 h. N = 3 each group. Error bars =±SEM. *P ≤ 0.05, **P ≤ 0.01 Significant difference between PGN+poly(I:C) treated with control/GSI.