Table 2 Statistics for associations of the three identified variables with the EV-D68 outbreak in 2014 USA, using an enlarged dataset from the NIAID Virus Pathogen Resource and both Pearson’s chi-square test and Fisher’s exact test.

From: Whole-Genome Sequence Analysis Reveals the Enterovirus D68 Isolates during the United States 2014 Outbreak Mainly Belong to a Novel Clade

Position (NY328)

Variant

Amino Acid

Group N

Group O

Total Strains

χ2

p-value

Fisher p-value

1817

C

Asn

23

4

62

40.14

2.4E-10

6.4E-12

T

Asn

1

34

3277

C

Thr

37

2

78

33.85

5.9E-09

7.4E-10

A

Asn

11*

28

4020

A

Ser

11

7

51

13.32

2.6E-04

1.4E-04

G

Gly

3

30

  1. *9 of 11 are from Italy 2014.