Figure 7 | Scientific Reports

Figure 7

From: An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids

Figure 7

A schematic representation of free and liposomally entrapped TPT (LTPT) compared to the metronomic dosing regimen of free TPT studied in TES.

Treatment response was determined by evaluating the changes in fluorescence intensity of TPT uptake, spheroid sizing of DIC (differential interference contrast) images and propidium iodide (PI) staining of dead/damaged cells.

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