Figure 2 | Scientific Reports

Figure 2

From: Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27

Figure 2

Cx43-Hsc70 interaction decreases nuclear accumulation of p27.

(a) Effect of Cx43-Hsc70 interaction on nuclear accumulation of p27. HuH-7 cells were transfected with Cx43-mRFP with or without T7-Hsc70. After 48 hr of transfection, immunofluorescence staining with anti-p27 antibodies was carried out. (b) Ratio of nuclear/cytoplasmic (N/C) fluorescence intensities in p27. Nucleocytoplasmic localization analysis in p27 was performed. At least 30 transfected cells were examined and quantified for each group and the data were plotted. The horizontal lines represent median values. *p < 0.05.

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