Figure 2
From: In-vitro Optimization of Nanoparticle-Cell Labeling Protocols for In-vivo Cell Tracking Applications
Efficiency of cell labeling with GNPs; microscopy images.
(a–c) TEM imaging of a cancer cell. (a) cancer cell without GNPs. (b,c) cancer cell loaded with GNPs, the white arrow points an accumulation of well-defined GNPs inside endosomes. (d,e) dark field microscopy of stem cells (d) without GNPs. (e) loaded with GNPs (Yellow-red). (f) Bright field microscopy of stem cells loaded with GNPs. (g–i) representative confocal images of cancer cell after 30 min incubation with fluorescent-coated glucose-GNPs complex. (g) bright field image of the cell. (h) fluorescent-coated glucose-GNPs (purple). (i) Bright field combined images. Images were taken at the midsection of the cell. Sections were imaged using Leica TCS SP5 with Acousto-Optical Beam Splitter microscope.
