Figure 1

Effects of adenine-induced tubulo-interstitial injury on body weight.
(a) Percentage body weight loss or gain (from day −10) in animals during adenine and methylcellulose treatment for 10 days, followed by 28 days of observation (•, GA, n = 12; ■, WA, n = 12; ○, GC, n = 9; □, WC, n = 6). Error bars have been removed to improve clarity of this graph. (b) Relative body weight loss of adenine treated animals (GA/WA) versus their methylcellulose controls (GC/WC) during adenine and methylcellulose treatment for 10 days, followed by 28 days of observation. Data are expressed as the mean ± standard deviation. *P > 0.05 between the adenine-treated groups.