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Figure 1

From: Photoacoustic “nanobombs” fight against undesirable vesicular compartmentalization of anticancer drugs

Figure 1

Conceptual schema and design of photoacoustic “nanobomb”.

(a) A schema showing typical chemoresistance pathway mediated by vesicular compartmentalization of anticancer drugs (Left panel) and a proposed chemosensitizing pathway that selectively disrupts undesirable vesicular sequestration using a photoacoustic “nanobomb” (Right panel). (b) TEM images of the SWCNTs. (c) Conjugation strategy of FA-SWCNTs and FA-SWCNTs-6G. (d) UV-VIS-NIR absorption spectrum of the SWCNTs in water; inset shows a photograph of the solution. (e) Illustration of the mechanism of photoacoustic shockwave generated by SWCNTs upon laser irradiation. (f) Generation of a photoacoustic signal after irradiation with a single laser pulse at a width of 5 ns and a power of 0.25 mJ per pulse.

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