Figure 3 | Scientific Reports

Figure 3

From: Complex folding and misfolding effects of deer-specific amino acid substitutions in the β2-α2 loop of murine prion protein

Figure 3

Graphs of quantitative parameters extracted from fitted fibrillisation curves for the 4 protein variants both without and with addition of preformed seed to drive the reaction.

(A) is a bar chart depicting the average lag time to fibrillisation whilst (B) represents the average rate of fibrillisation. Error bars are standard deviations and represent n > = 18 reactions for each variant. T-Test statistics (inset tables) test differences between lag times (A) or elongation rates (B).

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