Table 2 Correlations of Cognitive Tests with Plasma APL1β28 and Clusterin.

From: A correlativity study of plasma APL1β28 and clusterin levels with MMSE/MoCA/CASI in aMCI patients

 

aMCI Group (N = 47)

NC Group (N = 35)

APL1β28

Clusterin

APL1β28

Clusterin

MMSE, points

Unadjusted

0.046*(−0.293)

0.009**(−0.377)

0.871(−0.028)

0.584(−0.096)

Adjusted for age

0.047*(−0.295)

0.013*(−0.363)

0.423(0.142)

0.792(−0.047)

Adjusted for sex

0.059(−0.280)

0.011*(−0.372)

0.496(0.121)

0.886(−0.026)

Adjusted for education

0.055(−0.285)

0.005**(−0.404)

0.484(0.124)

0.808(−0.043)

Adjusted for ApoE ε4

0.053(−0.287)

0.008**(−0.386)

0.416(0.144)

0.834(−0.037)

Adjusted for BMI

0.025*(−0.363)

0.029*(−0.353)

0.466(0.132)

0.934(−0.015)

MoCA, points

Unadjusted

0.677(0.068)

0.012*(−0.392)

0.542(0.114)

0.870(−0.031)

Adjusted for age

0.707(0.062)

0.016*(−0.384)

0.526(0.120)

0.877(−0.030)

Adjusted for sex

0.605(0.085)

0.020*(−0.371)

0.618(0.095)

0.939(−0.015)

Adjusted for education

0.692(0.065)

0.020*(−0.372)

0.481(0.134)

0.966(0.008)

Adjusted for ApoE ε4

0.665(0.071)

0.016*(−0.385)

0.686(0.077)

0.897(−0.025)

Adjusted for BMI

0.489(0.127)

0.025*(−0.396)

0.608(0.100)

0.839(−0.039)

CASI, points

Unadjusted

0.164(−0.206)

0.017*(−0.346)

0.474(−0.125)

0.512(−0.115)

Adjusted for age

0.166(−0.208)

0.025*(−0.031)

0.500(−0.120)

0.508(−0.118)

Adjusted for sex

0.103(−0.244)

0.013*(−0.365)

0.433(−0.139)

0.665(−0.077)

Adjusted for education

0.136(−0.223)

0.021*(−0.340)

0.458(−0.132)

0.546(−0.107)

Adjusted for ApoE ε4

0.161(−0.210)

0.018*(−0.035)

0.318(−0.176)

0.484(−0.124)

Adjusted for BMI

0.188(−0.218)

0.055(−0.314)

0.466(−0.132)

0.583(−0.099)

  1. Data are presented as the p-value (correlation coefficient). P-values were obtained using partial correlation analysis to investigate the correlations between the cognitive test scores and plasma clusterin and APL1β28 levels, respectively. (*p < 0.05, **p < 0.01).