Figure 6
From: Screening and Identifying a Novel ssDNA Aptamer against Alpha-fetoprotein Using CE-SELEX
3-D structure and docking prediction.
(A) Three-dimensional structures of AP273 and AP211. The motifs of AP273 can be folded into 2 kinds of structures, AP273-1 and AP273-2. (B,C) A docking model between AP273-1 and AFP protein. In particular, dC9, dC10, dT11, dA13, dA19, dC20 are in close contact with AFP. C, T and A represent the bases and the number represents the location of the base in the ssDNA sequence. (C) A 3-D interacting mode observed from two views.
