Table 3 Average serum levels of proteins according to the clinical characteristics of the untreated tuberculosis patients.

From: Screening and identification of five serum proteins as novel potential biomarkers for cured pulmonary tuberculosis

Clinical characteristics (Cases)

ALB (mg/mL)

P a

ARHGDIB (pg/mL)

P a

C3 (μg/mL)

P a

FCN2 (μg/mL)

P a

LPA (μg/mL)

P a

Age

 

0.772

 

0.055

 

0.227

 

0.684

 

0.418

18–29 (21)

48.17 ± 32.71

 

80.11 ± 44.69

 

576.00 ± 781.00

 

18.78 ± 18.66

 

131.08 ± 118.21

 

30–49 (21)

49.57 ± 27.74

 

114.25 ± 93.23

 

558.80 ± 330.60

 

13.77 ± 20.77

 

126.48 ± 50.72

 

≥50 (15)

42.20 ± 28.97

 

126.82 ± 79.34

 

747.20 ± 333.60

 

14.30 ± 12.64

 

153.39 ± 46.36

 

Gender

 

0.948

 

0.164

 

0.755

 

0.579

 

0.389

Male (33)

47.35 ± 31.20

 

87.88 ± 92.27

 

614.40 ± 497.20

 

15.28 ± 14.69

 

135.15 ± 92.65

 

Female (24)

47.82 ± 30.96

 

110.33 ± 82.08

 

607.20 ± 582.40

 

13.85 ± 19.24

 

146.67 ± 89.79

 

Sputum smear

 

0.263

 

<0.001***

 

0.894

 

0.016*

 

0.495

Negative (21)

48.49 ± 18.76

 

147.87 ± 52.89

 

608.80 ± 325.20

 

10.32 ± 8.54

 

148.27 ± 38.30

 

Positive (36)

39.55 ± 31.14

 

71.16 ± 57.24

 

622.40 ± 860.00

 

19.65 ± 22.03

 

128.52 ± 159.35

 

Lung lesion

 

0.218

 

0.720

 

0.107

 

0.800

 

0.059

Single (21)

52.59 ± 28.29

 

89.22 ± 44.35

 

512.80 ± 483.20

 

16.18 ± 15.14

 

156.72 ± 119.18

 

Double (36)

44.19 ± 28.82

 

112.51 ± 97.18

 

622.40 ± 921.20

 

14.42 ± 19.91

 

126.48 ± 51.67

 

Chest X-ray

 

0.078

 

0.379

 

0.229

 

0.196

 

0.235

Non-cavity (47)

48.74 ± 26.96

 

88.27 ± 91.89

 

584.00 ± 460.00

 

14.18 ± 18.33

 

144.26 ± 96.74

 

Cavity (10)

28.67 ± 22.72

 

118.76 ± 48.04

 

931.60 ± 1116.20

 

20.76 ± 20.73

 

113.04 ± 54.11

 
  1. All data are presented as the median ± IQR. aP-value among groups, the Mann–Whitney U-test is used for two groups and the Kruskal-Wallis H-test is used for three groups. *P < 0.05, ***P < 0.001.