Figure 1
From: Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using 99mTc-HMPAO
Schematic diagram for radiolabeling method of 99mTc-HMPAO-exosome nanovesicles (ENVs).
99mTc-hexamethylpropyleneamineoxime (HMPAO) was chosen as one of the proper radiotracers for exosome labeling. After highly lipophilic 99mTc-HMPAO enters the ENVs, endogenous glutathione in ENVs begins to convert 99mTc-HMPAO to hydrophilic form, which is trapped inside ENVs.
