Figure 3
From: Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using 99mTc-HMPAO
In vivo SPECT/CT images of 99mTc-HMPAO-ENVs injected in mice.
After intravenous injection of 99mTc-HMPAO-ENVs or 99mTc-HMPAO, SPECT/CT images were acquired at 30 min, 3 hr and 5 hr in BALB/c mice. (a) The SPECT/CT imaging showed the significantly intense uptake of 99mTc-HMPAO-ENVs in the liver and radioactivity in the salivary glands and intestine until 5 hr. (b) In contrast, high brain uptake and the delayed salivary glands uptake were observed in 99mTc-HMPAO-injected mouse group.
