Figure 3

Most dysregulated genes involved in cell proliferation in the human degenerative annulus fibrosus.
The eight top dysregulated genes (p < 0.05, log2 fold ≥±1.5) were identified within the 77 significantly differently expressed genes (p < 0.05) involved in the cellular growth and proliferation. All the 6 genes up-regulated (red) and the 2 genes down-regulated (green) negatively affect cell proliferation.