Table 1 Microarray gene expression comparison of human annulus fibrosus cells.

From: Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus

Symbol

Description

p-value

Log2 fold

IGFBP3

Insulin-like growth factor binding protein 3

0.003

2.85

GREM1

Gremlin 1

0.002

2.54

PMAIP1

Phorbol-12-myristate-13-acetate-induced protein 1

0.010

2.49

GDF15

Growth differentiation factor 15

0.003

2.29

IFIT3

Interferon-induced protein with tetratricopeptide repeats 3

0.004

2.03

MGST1

Microsomal glutathione S-transferase 1

0.001

2.02

TFPI

Tissue factor pathway inhibitor

0.002

2.01

IFIT1

Interferon-induced protein with tetratricopeptide repeats 1

0.013

1.96

IFIT2

Interferon-induced protein with tetratricopeptide repeats 2

0.032

1.89

GBP1

Guanylate binding protein 1, interferon inducible

0.006

1.86

GPR64

G protein-coupled receptor 64

0.022

−1.59

SOD3

Superoxide dismutase 3, extracellular

0.002

−1.64

CHAD

Chondroadherin

0.020

−1.80

LOXL4

Lysyl oxidase-like 4

0.032

−1.83

LYVE1

Lymphatic vessel endothelial hyaluronan receptor 1

0.011

−1.85

BANK1

B-cell scaffold protein with ankyrin repeats 1

0.006

−2.09

IBSP

Integrin-binding sialoprotein

0.002

−3.46

  1. Significantly differentially expressed genes with p < 0.05, log2 fold cut off ≥±1.5 (degenerative (n = 16) versus non-degenerative (n = 8)).
Back to article page