Figure 1 | Scientific Reports

Figure 1

From: Synergistic anti-tumor therapy by a comb-like multifunctional antibody nanoarray with exceptionally potent activity

Figure 1

Scheme illustrated the design and fabrication of the comb-like anti-CD20 mAbs nanoarrays (PL-RB).

(a) The type I and II Rituximab and 11B8 were grafted to the single long polymer chain PEI. (b) The EPR effect of nano seized PL-RB. (c) The cellular interaction between PL-RB and antigens resulted in intra-/inter- cellular corsslinking. (d) The synergetic therapeutic mechanism of CDC, ADCC, PCD induced by PL-RB.

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