Figure 3

Proteasome inhibitor BTZ suppresses the aortic wall remodeling in Ang II-infused apoE−/− mice.
(a) The representation of H&E staining in abdominal aorta from Apo E−/− mice (left). Bar graph shows the quantification of aortic wall thickness (right; n = 3 per group). (b) The representation of elastin staining in abdominal aorta from Apo E−/− mice. Magnification:×100. Scale bar: 50 μm. Data expressed as mean ± S.E.M. **P < 0.01 vs Saline, ##P < 0.05 vs Ang II. L: lumen.