Figure 4

Proteasome inhibitor BTZ decreases MMP activity in Ang II-infused apoE−/− mice.
(a,b) The qPCR analysis for the mRNA expression of MMP-2 and MMP-9 in abdominal aorta from four groups. GAPDH was used as an internal control. (c) The representation of MMP zymography gel (the upper panel). The analysis for the brightness of the bands (the lower panel). (n = 4 per group). Data expressed as mean ± S.E.M. *P < 0.05 vs Saline, **P < 0.01 vs saline, #P < 0.05 vs Ang II.