Table 1 Characteristics of the seven studies included in meta-analysis.

From: Notching early repolarization pattern in inferior leads increases risk of ventricular tachyarrhythmias in patients with acute myocardial infarction: a meta-analysis

First

Location

Patients

ER(+)

Study

ER definition

The variables of

Endpoints

Follow-up

Quality

author

(n)

n(%)

design

multivariate model

score

(Year)

Identification of ER before AMI

 Naruse et al.7 (2012)

Japan

220

34 (16)

Cohort

An elevation of the QRS-ST junction of >0.1 mV from baseline in at least 2 inferior or lateral leads, manifested as QRS slurring or notching

Age per year, male sex, time from the symptom onset to emergency room of <180 minutes, Killip class >1, peak CK levels >3000 U/L, No. of diseased coronary arteries >1, STEMI, hypertension, diabetes mellitus, smoking

Sustained VF

48 hours

9

 Kim et al.12(2014)

Korea

296

52 (17.6)

Cohort

J point elevations manifested through QRS notching or slurring for at least 1 mm (0.1 mV) above the baseline in at least two consecutive inferior or lateral leads

Unadjusted

VF

48 hours

9

 Patel et al.8(2012)

America

100

30 (30)

Case-control

Notching, slurring, or J-point elevation ≥0.1 mV above baseline in ≥2 contiguous inferior, lateral, or anterior leads

LVEF

VTAs(Non-sustained VT, Sustained VT, VF)

72 hours

9

 Diab et al.13(2014)

Egypt

102

43 (42.2)

Case-control

≥1 mm J point elevation with or without ST segment elevation.

LVEF, QTc and QTd

VTAs(Sustained VT, VF)

48 hours

8

Identification of ER after AMI

 Özcan et al.10 (2014)

Turkey

521

61 (11.7)

Cohort

Elevation of the J-point (QRS–ST Junction) above 0.1 mV relative to QRS onset in two or more inferior leads (DII–DIII-aVF), limb lateral leads (DI-aVL), or left precordial leads (V4–V6)

Unadjusted

VTAs(Sustained VT, VF)

30 days

8

 Park et al.11 (2014)

Korea

266

76 (28.6)

Cohort

J-point elevation ≥0.1 mV and “notching” and “slurring” of the terminal part of the QRS complex in at least 2 lateral or inferior leads.

Inferior MI, E/E′, LVEF (<45%)

VTAs(Non-sustained VT, Sustained VT, VF)

6.7 ± 4.5 days

8

 Rudic et al.9 (2012)

Germany

60

18 (30)

Case-control

J-point elevation ≥0.1 mV and “notching” and “slurring” of the terminal part of the QRS complex in at least 2 lateral or inferior leads.

LVEF and QTc

VF

During hospitalization

7

  1. ER = early repolarization; STEMI = ST-elevation myocardial infarction; AMI = acute myocardial infarction; CK = creatine kinase; LVEF = left ventricular ejection fraction; VF = ventricular fibrillation; VT = ventricular tachycardia; VTAs = ventricular tachyarrhythmias.