Figure 8
From: The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload
Estimation of eccentric hypertrophy during VO using physiological parameters LVEDP and LVDd.
(a) Schematic diagram to estimate HW from LVEDP and LVDd. (b) LVEDP (left panel) and LVDd (right panel) curves were reproduced with Simulink from resampled data points. (c) Estimated mTOR activity during VO. (d) Estimated HW during VO when α = 0.001. (e) Correlation between measured and estimated HW. Data are shown as the mean ± SEM (n = 4).
