Figure 1 | Scientific Reports

Figure 1

From: The C-terminal region of the non-structural protein 2B from Hepatitis A Virus demonstrates lipid-specific viroporin-like activity

Figure 1

(A) Hydrophobicity plot of poliovirus 2B, coxsackievirus 2B and the C-terminal of HAV 2B. The corresponding helical wheel representations for the first amphipathic helix in the alpha-helical hairpin region of poliovirus 2B (35-52 residues), coxsackievirus 2B (37-54 residues) and HAV 2B (176-193 residues) are shown and sequences corresponding to the hairpin regions (Hydrophobic Regions HR1 and HR2 respectively) are provided. (B) Circular Dichroism (CD) spectroscopy of the 2B peptide at 5 μM in phosphate buffer, pH 7.0, with or without 50% TFE.

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