Figure 4 | Scientific Reports

Figure 4

From: The C-terminal region of the non-structural protein 2B from Hepatitis A Virus demonstrates lipid-specific viroporin-like activity

Figure 4

(A) The mean hydrodynamic radius or Rh (mean) of liposomes mimicking ER vesicles in buffer, or after 20 minutes of incubation with 1% Triton X-100, or 5 μM of the 2B peptide. (B) Extent of release of fluorescent-dye labeled dextrans of various sizes from liposomes mimicking ER vesicles, by the 2B peptide at pH 7.0. Data are represented as the means of the results for triplicate independent samples ± the standard deviation (SD). ***P < 0.001; **P < 0.01; *P < 0.05; ns, not significant (Student’s t test in comparison with results for rhodamine dye release in endoplasmic reticulum).

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