Figure 2
From: Diversity of key players in the microbial ecosystems of the human body
Significantly central groups of OTUs in different ecosystems (groups represented in columns and locations represented in rows).
(a) The presence of dark blue and light blue boxes means that the type of OTU (in column) is significantly (hypergeometric test, p < 0.05) over-represented in the top 20% of the degree-based centrality rank of the interaction network of the body part (in row). If we look at the top 5% or 10% of the degree centrality rank, we may have a different set of over-represented OTU groups: red groups become over-represented, light blue groups are not over-represented anymore and dark blue groups not sensitive (remain over-represented). (b) If we quantify positional importance by betweenness centrality instead of degree centrality, azure groups become over-represented, light blue groups are not over-represented anymore and dark blue groups not sensitive (remain over-represented). Here, dark blue and light blue boxes correspond to the “degree/top 20%” combination. (c) Here we show groups that are not significantly central but clearly important, simply because of being dominant (in green): these groups provide at least 10% of the total number of OTUs. Dark blue boxes show groups that are both dominant and significantly over-represented. Light blue boxes show groups that are significantly over-represented but not dominant in this sense.
