Table 2 Groups of OTUs composing the interaction network of the stool ecosystem.

From: Diversity of key players in the microbial ecosystems of the human body

stool

total

20%

D_P

B

B_P

10%

D_P

5%

D_P

D

D

D

Akkermansia

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Alistipes

72

4

0,9996

3

0,9999

1

0,9961

0

0,9781

Anaerotruncus

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Bacteroidales

4

0

0,5912

0

0,5912

0

0,3433

0

0,1865

Bacteroides

640

157

0,0000

164

0,0000

67

0,2426

24

0,9764

Bifidobacterium

2

0

0,3604

0

0,3604

0

0,1895

0

0,0980

Blautia

20

1

0,9326

1

0,9326

1

0,6085

1

0,2658

Clostridiales

13

2

0,4995

1

0,7683

1

0,3775

1

0,1358

Clostridium

21

3

0,6321

1

0,9440

2

0,3497

0

0,6643

Coprococcus

9

0

0,8670

0

0,8670

0

0,6126

0

0,3721

Dialister

7

0

0,7915

0

0,7915

0

0,5214

0

0,3035

Faecalibacterium

94

37

0,0000

34

0,0000

25

0,0000

19

0,0000

Holdemania

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Lachnospira

12

0

0,9323

0

0,9323

0

0,7180

0

0,4628

Lachnospiraceae

50

5

0,9554

5

0,9554

1

0,9681

1

0,7292

Odoribacter

10

0

0,8938

0

0,8938

0

0,6515

0

0,4039

Oscillospira

51

14

0,0670

12

0,2032

8

0,0593

5

0,0385

Parabacteroides

65

0

1,0000

1

1,0000

0

0,9991

0

0,9680

Porphyromonadaceae

3

0

0,4886

0

0,4886

0

0,2704

0

0,1434

Rikenellaceae

3

0

0,4886

0

0,4886

0

0,2704

0

0,1434

Roseburia

40

3

0,9735

4

0,9277

1

0,9219

0

0,8770

Ruminococcaceae

27

4

0,6550

3

0,8212

4

0,1230

2

0,1502

Ruminococcus

43

2

0,9959

2

0,9959

0

0,9899

0

0,8952

Subdoligranulum

36

18

0,0000

20

0,0000

14

0,0000

10

0,0000

Alcaligenaceae

7

0

0,7915

0

0,7915

0

0,5214

0

0,3035

Burkholderiales

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Catabacteriaceae

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Dorea

1

1

0,0000

0

0,2002

0

0,0997

0

0,0502

Lachnobacterium

2

0

0,3604

0

0,3604

0

0,1895

0

0,0980

Sutterella

2

0

0,3604

0

0,3604

0

0,1895

0

0,0980

Turicibacteraceae

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Eubacterium

6

0

0,7390

0

0,7390

0

0,4681

0

0,2665

Phascolarctobacterium

6

0

0,7390

0

0,7390

0

0,4681

0

0,2665

Collinsella

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

Escherichia

1

0

0,2002

0

0,2002

0

0,0997

0

0,0502

  1. The column “total” shows how many individual OTUs belong to a particular group. Column “D” shows the number of OTUs being part of the top 20% of the centrality rank based on degree centrality and column “D_P” shows whether it is significant according to a hypergeometric test. We also show the same results based on betweenness centrality (B, B_P) as well as the degree-based results for the top 10% and 5% of the centrality rank (significant values always shaded). This network is composed of 1254 OTUs so the top 20% means 251 OTUs. Among them, there are 14 Oscillospora OTUs out of the 51 total Oscillospora OTUs, this is not significant. In the top 5% we only have 63 OTUs and the 5 Oscillospora OTUs in this top 5% is already significantly over-represented compared to random. Note that Dorea is technically speaking significant (1 out of 1 OTU in top 20%) but this should be considered with care. Similar results for other body parts are shown in Supplementary Material A.
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