Table 1 Nucleotide and amino acid changes in wild-type and mouse-adapted influenza virus B/Florida/04/2006.

From: Mouse adaptation of influenza B virus increases replication in the upper respiratory tract and results in droplet transmissibility in ferrets

Gene segment

Changed nucleotidesa

Changed amino acidsb

Position

Original

Mouse- adapted

Position

Original

Mouse-adapted

HA

951

T

A

317

P

—

 

1271

A

G

424

D

G

M1c

719

A

C

240

N

T

BM2c

27

C

T

9

I

—

NP

40

A

G

14

N

S

 

882

G

C

294

K

N

PA

1825

G

A

609

V

I

  1. aNumbering of nucleotides is relative to B/Lee/40 and begins at the start of the non-coding region of the RNA segment.
  2. bNumbering of amino acids is relative to B/Lee/40 and begins at the start of the coding region.
  3. cRNA segment 7 encodes two polypeptides, M1 and BM2, using tandem cistrons.
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