Figure 5 | Scientific Reports

Figure 5

From: Long Non Coding RNA MALAT1 Promotes Tumor Growth and Metastasis by inducing Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma

Figure 5

MALAT1 knockdown inhibited tumor growth in a xenograft model in vivo.

(a) The image of Tscca xenograft tumors treated with si-NC and si-MALAT1. (b) Tumor growth curve indicated that MALAT1 siRNA injection treatment inhibited significantly Tscca xenograft tumor growth (P < 0.05). (c) Average tumor weight of si-MALAT1 group was reduced compared to the control and si-NC groups (P < 0.05). (d) IHC staining showed the expression of Ki-67, MMP-2, MMP-9, N-cadherin and Vimentin were inhibited in the MALAT1 siRNA-treated Tscca xenograft tumors (original magnification: 200×).

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