Table 2 Characteristics of Prospective Studies on Weight Gain and Hip Fracture.

From: The relationship between weight change and risk of hip fracture: meta-analysis of prospective studies

Source

No. of participants

Location/Period

Gender

Age (years)

No. of casesa

Measure/Range of Loss

Study Qualityb

Adjustment for Covariatesc

Langlois et al. 1998

2413

United States 1985–1986

M

67–104

72 HF

Weight Gain: Q1≤5% 5%<Q2<10% Q3≥10%

7

BMI at age 50 year, number of medical conditions, low mental status score, physical disability.

Meyer et al. 1998

39089

Norway 1974–1978

F:19938 M:19151

37–58

207HF

Weight Gain(kg/12 years): F:Q1: Loss of 1.3 to gain of 1.5 Q2: Gain of 1.6 to 4.6 Q3:Gain of ≥ 4.7 M:Q1: Loss of 0.9 to gain of 2.0 Q2: Gain of 2.1 to 5.2 Q3:Gain of ≥5.3

9

Age at screening, weight variability (root mean square error), mean body mass index, body height, self-reported physical activity at work and during leisure, diabetes mellitus, disability pension, marital status and smoking habits.

Amador et al. 2006

1749

United States 1993–2001

F: 1008 M: 741

≥65

18HF

Weight Gain: Q1≤10% Q2>10%

7

Sociodemographic variables included age and gender, smoking status, medical conditions, depressed symptomatology, BMI, waist circumference, grip strength.

French et al. 1996

33834

United States 1986–1992

F

55–69

182HF

Weight Gain: Q1<10% Q2>10%

7

Baseline values of age, waist/hip ratio, BMI, BMI2, smoking status (never, former, current), pack years of cigarettes, education (<high school, high school, >high school), physical activity (low, medium, high), alcohol (0, <4, ≥4 g/d), marital status (yes/no), hormone replacement (never, former, current).

Langlois et al. 1996

3683

United States 1983–1992

F

67–104

253HF

Weight Gain: Q1≤5% 5%<Q2<10% Q3≥10%

8

Age at baseline, body mass index at age 50 years, cigarette smoking, alcohol consumption in the past year, number of medical conditions, impaired mobility and use of thiazide diuretics.

  1. aHF: Hip fracture.
  2. bStudy quality was judged based on the Newcastle-Ottawa Scale (range, 1–9 stars).
  3. cBMI: body mass index; BMD: bone mineral density.