Figure 2 | Scientific Reports

Figure 2

From: Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer

Figure 2

Tumor-associated stromal content contributes to defining Mesenchymal and Immunoreactive subtypes.

(A) Tumor purity estimated by ABSOLUTE analysis for four molecular subtypes of TCGA samples. (B) ESTIMATE scores for four molecular subtypes of TCGA samples. (C) GSEA for upregulation of Mesenchymal and Immunoreactive genes in microdissected tumor stroma versus epithelial tissues. (D) GSEA for downregulation of Mesenchymal and Immunoreactive genes in patient-derived xenografts (PDX) versus matched primary tumors.

Back to article page