Figure 4
Process of mutation filtering.
Among 10161 variants identified from 63 samples, there were 8994 variants that were synonymous or from non-coding flanking regions, 1102 SNPs reported by dbSNP or 1000 Genome Project with allele frequency greater than 0.1%, 20 mutations with low mapping quality score. After filtering out above variants 45 variants were identified in the end and listed in Table 1, including 38 SNVs and 7 indels. The MAF of these SNVs ranges from 43.4% to 60.0%, indicating that all of them are heterozygous germline mutations.
