Figure 6

In vivo effects of cyclophosphamide (CTX) and E5 on infiltration of HL-60 cells into spleen and liver.
(A) The weight and size of spleens in healthy mice (without HL-60 transplantation) and CTX-monotreated or combination treated AML mice. (B) Histologic sections of spleen and liver in each group of mice were stained with H&E. Images of each organ in the second line are the amplification of images in the first line. Red arrows represent normal cells and blue arrows represent HL-60 cells infiltrated in spleens. Yellow arrows represent HL-60 cells infiltrated into livers.