Table 1 List of compounds promoting the neuronal differentiation of ReNCell VM cells.

From: A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cells

Compound name

Compound description

4F 4PP oxalate

selective 5-HT2A antagonist

BIO

ATP-competitive GSK-3 inhibitor.

BWB70C

selective inhibitor of 5-lipoxygenase

Canrenone

aldosterone antagonist

DMPO

neuroprotective agent, radical spin trap

Ezetimibe

Inhibit cholesterol absorption in the small intestine

Flunixin meglumine

non-steroidal anti-inflammatory

Fluvastatin

HMG-CoA reductase inhibitor

Indirubin-3′-oxime

GSK-3 inhibitor; also inhibits other protein kinases

Isoproterenol hydrocloride

selective β-adrenoceptor agonist

Kenpaullone

GSK-3 inhibitor; CDK inhibitor

Mevastatin

HMG-CoA reductase inhibitor

n-methyl-metacryloyl-lupinine

quinolizidine alkaloid extracted from plant

Phenoxybenzamine hydrochloride

selective α-adrenoceptor blocking agent; calmodulin antagonist

SB 203580

selective inhibitor of p38 MAPK

SB 239063

potent, selective p38 MAPK inhibitor; orally active

SB 415286

competitive GSK-3 inhibitor.

Sotalol hydrochloride

β-adrenoceptor agonist

Spermine tetrahydrochloride

modulatory on the NMDA glutamate receptor

TCS 2002

GSK-3 inhibitor

Tolazoline hydrochloride

non-selective competitive α-adrenoceptor antagonist