Table 2 List of compounds promoting the dopaminergic neuronal differentiation of ReNCell VM cells.

From: A High-content screen identifies compounds promoting the neuronal differentiation and the midbrain dopamine neuron specification of human neural progenitor cells

Compound name

Compound description

1-Naphthyl PP1

Src family kinase inhibitor; also inhibits c-Abl

7-NINA

non-selective NOS inhibitor

AG 490

EGFR-kinase inhibitor; JAK2/3 inhibitor

Bifonazole

inhibit ergosterol synthesis; inhibit HMG-CoA

Cilostamide

selective inhibitor of PDE III

Clobenpropit dihydrobromide

highly potent H3 antagonist and H4 partial agonist

D 4476

CK1 inhibitor; TGF-βRI inhibitor

DAPT

γ-secretase inhibitor

HA14-1

Bcl-2 inhibitor

ICI 118,551 hydrochloride

highly selective β2-adrenoceptor antagonist

ICI-185,282

potent thromboxane receptor antagonist

Kynurenic acid

broad spectrum EAA antagonist

LY 364947

selective inhibitor of TGF-βRI

Mevastatin

HMG-CoA reductase inhibitor

MK-912

selective α2A-adrenoreceptor agonist

Naltrindole hydrochloride

non-peptide δ opioid antagonist

Nefazodone HCl

5-HT2, 5-HT1A receptor antagonist

ODQ

selective inhibitor of NO-sensitive guanylyl cyclase

Pranoprofen

non-steroidal anti-inflammatory

Pravastatin

inhibit HMG-CoA reductase

Prochlorperazine edisylate

D2 receptor antagonist

Purpurin

xanthin oxidase inhibitor

R(–)-Isoproterenol (+)-bitartrate

selective β-adrenoceptor agonist

R(+)-Terguride

dopamine receptor agonist.

SLV 320

potent and selective A1 antagonist

S-Sulfo-L-cysteine sodium salt

EAA receptor agonist

SU 5416

potent and selective VEGFR PTK inhibitor

Tyrphostin AG 112

protein tyrosine kinase inhibitor

Tyrphostin AG 494

protein tyrosine kinase inhibitor

Tyrphostin B44

EGFR-kinase inhibitor