Figure 1 | Scientific Reports

Figure 1

From: IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

Figure 1

Gene set variation analysis (GSVA) of differentially activated gene sets identified inhibition of hypoxia, vasculo- and angiogenesis signaling pathways in IDH-1/2 mutant tumors and activation in IDH-1/2 wild-type tumors.

Rows represent samples of 288 patients with low-grade diffuse or anaplastic gliomas from The Cancer Genome Atlas (TCGA). Columns represent GSVA enrichment scores for the individual gene set.

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