Table 2 rCBV histogram analysis for differentiating IDH-1/2 mutant and wildtype tumors.

From: IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

Percentile

Mann-Whitney U test

Logistic regression

p-value

z-score

OR

(95% CI)

p-value

AUC

(95% CI)

Correctly classified

PPV

NPV

5

0.00

3.46

0.07

(0.01–0.94)

0.05

66.7%

(50.2%–83.2%)

82.2%

82.9%

66.7%

10

0.05

1.93

0.08

(0.01–0.55)

0.01

71.6%

(55.8%–87.3%)

83.6%

84.1%

75.0%

15

0.01

2.49

0.08

(0.01–0.43)

0.00

74.8%

(60.1%–89.6%)

82.2%

83.8%

60.0%

25

0.00

2.87

0.09

(0.02–0.41)

0.00

79.9%

(67.5%–92.3%)

82.2%

83.8%

60.0%

50

0.00

4.11

0.17

(0.04–0.76)

0.02

85.5%

(75.2%–95.8%)

83.6%

86.2%

62.5%

75

0.00

4.40

0.23

(0.06–0.88)

0.03

88.0%

(77.2%–98.9%)

86.3%

87.7%

75.0%

90

0.00

4.89

0.31

(0.130.78)

0.01

92.2%

(84.3%100.0%)

87.7%

89.1%

77.8%

95

0.00

4.88

0.40

(0.22–0.75)

0.00

92.2%

(84.8%–99.7%)

86.3%

88.9%

70.0%

99

0.00

4.72

0.56

(0.42–0.76)

0.00

90.8%

(83.9%–97.7%)

82.2%

85.9%

55.6%

  1. Abbreviations: AUC = Area under the curve; CI = confidence interval; NPV = negative predictive value; OR = Odds ratio; PPV = positive predictive value.