Table 2 rCBV histogram analysis for differentiating IDH-1/2 mutant and wildtype tumors.
Percentile | Mann-Whitney U test | Logistic regression | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
p-value | z-score | OR | (95% CI) | p-value | AUC | (95% CI) | Correctly classified | PPV | NPV | |
5 | 0.00 | 3.46 | 0.07 | (0.01–0.94) | 0.05 | 66.7% | (50.2%–83.2%) | 82.2% | 82.9% | 66.7% |
10 | 0.05 | 1.93 | 0.08 | (0.01–0.55) | 0.01 | 71.6% | (55.8%–87.3%) | 83.6% | 84.1% | 75.0% |
15 | 0.01 | 2.49 | 0.08 | (0.01–0.43) | 0.00 | 74.8% | (60.1%–89.6%) | 82.2% | 83.8% | 60.0% |
25 | 0.00 | 2.87 | 0.09 | (0.02–0.41) | 0.00 | 79.9% | (67.5%–92.3%) | 82.2% | 83.8% | 60.0% |
50 | 0.00 | 4.11 | 0.17 | (0.04–0.76) | 0.02 | 85.5% | (75.2%–95.8%) | 83.6% | 86.2% | 62.5% |
75 | 0.00 | 4.40 | 0.23 | (0.06–0.88) | 0.03 | 88.0% | (77.2%–98.9%) | 86.3% | 87.7% | 75.0% |
90 | 0.00 | 4.89 | 0.31 | (0.13–0.78) | 0.01 | 92.2% | (84.3%–100.0%) | 87.7% | 89.1% | 77.8% |
95 | 0.00 | 4.88 | 0.40 | (0.22–0.75) | 0.00 | 92.2% | (84.8%–99.7%) | 86.3% | 88.9% | 70.0% |
99 | 0.00 | 4.72 | 0.56 | (0.42–0.76) | 0.00 | 90.8% | (83.9%–97.7%) | 82.2% | 85.9% | 55.6% |